A core outcome set for pituitary surgery research: an international delphi consensus study
Authors' conclusion
We advocate for use of the COS in future pituitary surgery research.
Study context
- Population
- Healthcare professionals (HCPs), patients and caregivers; 33 outcomes from a systematic review of pituitary adenoma surgery outcomes and a study on patient-reported measures
- Participants
- 95 first-round responses
- Outcome
- Core outcome set for pituitary surgery research (outcomes with a median score of 5 included)
Methodological detailsinternational, two-round online survey, live online consensus meeting, Live meeting attended by 12 participants: 5 HCPs, 6 patients, 1 caregiver; voted on borderline outcomes (median scores 3-4)
- International
- Two-round online survey
- Live online consensus meeting
- Live meeting attended by 12 participants: 5 HCPs, 6 patients, 1 caregiver; voted on borderline outcomes (median scores 3-4)
Recommendations
As reported in the abstract
Final COS
- Consensus reached on final core outcome set (COS) of 7 domains: short-term surgical; nasal; ophthalmic; endocrine; quality of life and psychological; other short-term; disease control outcomes
Further findings
Round 1 median scores of 33 outcomes
- Median score 5
- 16
- Median score 4.5
- three
- Median score 4
- 14
- 95 responses (52% HCPs, 48% patients/caregivers)
Round 2 median scores of 33 outcomes
- Median score 5
- 14
- Median score 4.5
- two
- Median score 4
- 15
- Median score 3
- two
- 87 responses (52% HCPs, 48% patients and caregivers)
Original publication
A core outcome set for pituitary surgery research: an international delphi consensus study. Pituitary. Published 23 July 2025. doi:10.
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