Osteoporosis, bone & mineral

A comparison of foot fractures relative to other fragility fractures: a review and analysis of the American Orthopaedic Association’s Own the Bone Database

Osteoporos IntPublished Retrospective cohort study

Authors' conclusion

Foot fragility fracture patients are more likely to be female and younger compared to patients with a non-foot fragility fracture. A foot fragility fracture is a sentinel event considering that a prior foot fragility fracture is strongly predictive of a subsequent foot fragility fracture.

Study context

Population
Patients with fragility fractures in the American Orthopaedic Association's Own the Bone database, January 2009 to March 2022
Participants
58,001 fragility fractures
Exposure
Foot fragility fracture vs non-foot fragility fracture
  • Foot fragility fracturen = 750
  • Non-foot fragility fracturen = 57,251reference
Outcome
Characteristics of patients with isolated foot fragility fracture vs non-foot fragility fracture
Methodological detailssecondary cohort comparative analysis, Own the Bone (OTB) database
  • Secondary cohort comparative analysis
  • OTB database

Main finding

As reported in the abstract

Patient characteristics
GroupValueFemaleBMI
Foot fragility fracture66.9 years old91.5%28.3 kg/m²

Foot fragility fracture

Value66.9 years old
Female91.5%
BMI28.3 kg/m²
  • Foot fragility fracture vs Non-foot fragility fracture: P < 0.0001 — younger, more often female, higher BMI

Observational data: associations, not effects.

Further findings

OutcomeOR (CI)P value
Prior foot fragility fracture9.119 (7.44–11.18)P < 0.001

Future foot fragility fracture

Young, female patients with a prior foot fragility fracture at higher risk of a future foot fragility fracture; risk increased as BMI increased

Original publication

A comparison of foot fractures relative to other fragility fractures: a review and analysis of the American Orthopaedic Association’s Own the Bone Database. Osteoporos Int. Published 18 June 2024. doi:10.1007/s00198-024-07153-x

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