A Comparison of Depressive Symptom Presentation in Adolescent Type 1 Diabetes and Pediatric Primary Care Samples
Main finding · Higher total PHQ-9 scoreResult — go to the resultOdds ratio 1.51 95% CI 1.17–1.98Authors' conclusion
Symptom endorsement for sleep and fatigue were higher for adolescents with T1D and without T1D. Study results support the need for further examination of the origins of somatic symptoms in T1D and for an additional examination of the specificity of depression screening instruments used in routine pediatric diabetes care.
Study context
- Population
- Adolescents 13–18 years screened for depressive symptoms with PHQ-9, US; 53.5% male, 71.7% White, median age 13.0matched case-control
- Participants
- 477 vs 477
- Comparison
- Adolescents with T1D vs pediatric primary care sample
- T1Dn = 477
- Primary caren = 477reference
- Outcome
- Depression screening response patterns (total PHQ-9 score)
Methodological detailsage, sex and race-matched, electronic health records
- Age, sex and race-matched
- Electronic health records
Main finding
Higher total PHQ-9 score
Odds ratio
1.51
95% CI 1.17–1.98
P = 0.002
T1Dvs Primary care
OR 1.51 (95% CI 1.17–1.98); P = 0.002
As reported in the abstract
Observational data: associations, not effects.
Further findings
| Outcome | OR (95% CI) | P value | |
|---|---|---|---|
| Higher somatic subscoreAdjusted for type of insurance | 1.57 (1.20–2.05) | P = 0.001 | |
| 0.512Odds ratio (log scale) |
Item endorsement greater than "not at all"
- T1D more likely to have higher values for somatic items such as "trouble falling asleep" and "feeling tired" vs primary care
Item-total correlations and Cronbach's α
- All items contributed to the overall score in the same manner in each group
Original publication
A Comparison of Depressive Symptom Presentation in Adolescent Type 1 Diabetes and Pediatric Primary Care Samples. Pediatr Diabetes. Published 23 August 2023. doi:10.
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