24-hour activity composition is associated with lower fall and fracture risk in older men
Authors' conclusion
When accounting for the co-dependence of daily activities, higher proportions of SB relative to the proportion of PA and sleep were associated with higher odds of recurrent falls and fracture risk.
Study context
- Population
- Older men aged 78.9 ± 5.1 yr in the Osteoporotic Fractures in Men (MrOS) Study
- Participants
- 2,918 men
- Exposure
- Proportions of time in physical activity (PA), sedentary behavior (SB) and sleep relative to the remaining behaviors
- Outcome
- Recurrent falls (2+ falls in any yr), any fractures and MOF
Methodological detailscompositional data analysis, accelerometer-measured 24-h activity, Accelerometers worn on right tricep for seven consecutive 24-h periods; PA >1.5 METs, SB ≤1.5 METs, Generalized estimating equations for recurrent falls; Cox regression for any fracture and major osteoporotic fracture (MOF)
- Compositional data analysis
- Accelerometer-measured 24-h activity
- Accelerometers worn on right tricep for seven consecutive 24-h periods; PA >1.5 METs, SB ≤1.5 METs
- Generalized estimating equations for recurrent falls; Cox regression for any fracture and MOF
Main finding
As reported in the abstract
Recurrent falls, any fracture and MOF by 24-h activity composition · falls over 4 yr; fractures over 10 ± 4 yr
- Recurrent falls, overall
- 1025 (35.2%)
- Incident fractures, overall
- 669 (22.9%)
- MOF, overall
- 370 (12.7%)
- Higher PA relative to SB and sleep: recurrent falls, OR
- 0.87 (0.76-0.99) (95% CI)
- Higher SB relative to PA and sleep: recurrent falls, OR
- 1.38 (1.06-1.81) (95% CI)
- Higher SB relative to PA and sleep: any fracture, HR
- 1.42 (1.05-1.92) (95% CI)
- Higher sleep relative to PA and SB: fracture, HR
- 0.74 (0.54-0.99) (95% CI)
Observational data: associations, not effects.
Original publication
24-hour activity composition is associated with lower fall and fracture risk in older men. J Bone Miner Res. Published 30 September 2024. doi:10.
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