11-Oxygenated Androgen Metabolite Concentrations Are Affected by Pubertal Progression and Obesity
An erratum to this article was published (Horm Res Paediatr, 2023 ↗)
Authors' conclusion
Beyond adrenarche, 11-oxyandrogens continue to rise during pubertal development. The differences in 11KT trajectories in males and females are small compared to changes in testosterone for males and estradiol for females during puberty. Obesity appears to influence the trajectories of 11-oxyandrogens during puberty.
Study context
- Population
- Healthy youth, males and females, classified by Tanner stage and body mass index (BMI)
- Participants
- 249 participants6 prior studies
Primary result
As reported in the abstract
Serum 11-oxyandrogens (11OHA4, 11OHT, 11KT) across puberty
- 11OHA4 and 11OHT increased modestly between early and late puberty in youth with normal weight
- p < 0.05
- Increases in 11KT did not reach statistical significance
- p < 0.06
- 11KT levels differed between sexes throughout puberty
- p < 0.01
- Trajectories of 11KT and 11OHA4 throughout puberty differed by BMI category
- p < 0.05
Original publication
11-Oxygenated Androgen Metabolite Concentrations Are Affected by Pubertal Progression and Obesity. Horm Res Paediatr. Published 29 November 2022. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →