Weight Gain and Glycemic Control in Adults with Type 1 Diabetes in the T1D Exchange Registry
Authors' conclusion
Significant weight gain in adults with T1D who had good to adequate glycemic control was associated with modest deterioration in glucose control despite an increase in TDD.
Study context
- Population
- Adults aged ≥25 years with T1D in the T1D Exchange Registry; those who lost >5 lb excluded; mean age 45 ± 13 years, 57% female, 92% White non-Hispanic
- Participants
- 1,969 adults
- Exposure
- Weight gain categories vs stable weight from registry enrollment to year 5
- Outcome
- HbA1c and total daily insulin dose (TDD)
- Follow-up
- Year 5
Methodological detailsLinear regression models
- Linear regression models
Main finding
As reported in the abstract
HbA1c, enrollment HbA1c <8.0%
P = 0.005
Observational data: associations, not effects.
Further findings
Mean, %
| Outcome | Stable weight | Gained ≥20 lb | P value |
|---|---|---|---|
| HbA1c, enrollment HbA1c ≥9.0% · year 5Gained ≥20 lb vs Stable weight · statistically insignificant | 9.2 (SD 1.7%) | 8.4 (SD 1.3%) | P = 0.09 |
Original publication
Weight Gain and Glycemic Control in Adults with Type 1 Diabetes in the T1D Exchange Registry. Diabetes Technol Ther. Published 1 February 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →