Vaccinome Landscape in Nearly 620 000 Patients With Diabetes
Authors' conclusion
Immunization coverage is still far from the recommended targets in patients with diabetes. Despite this, influenza vaccination protected nearly 3800 per 100 000 patients with diabetes from risk of death. The overall impressive decrease in mortality and hospitalizations observed in vaccinated patients strengthens the need for scaling up the "vaccinome" landscape in patients with diabetes.
Study context
- Population
- Patients with diabetes (T1D and T2D), Lombardy Region (Italy), September 2021–September 2022; 9,534,087 subjects without diabetes also assessed
- Participants
- 618,396 patients
- Exposure
- Vaccinated vs unvaccinated patients with diabetes
- Outcome
- Immunization coverage among patients with diabetes
Methodological detailspopulation-based registry
- Population-based registry
Main finding
As reported in the abstract
Influenza vaccine
44.6%
Pneumococcal vaccine
10.9%
Antimeningococcus vaccine
2.5%
Antizoster vaccine
0.7%
Observational data: associations, not effects.
Further findings
Mortality and hospitalizations after influenza, zoster, and meningococcus immunization
- Overall reduction in mortality risk
- 2-fold
- Decrease in hospitalizations
Mortality and cardiac/pulmonary hospitalizations in older patients with diabetes
- Lower risk of mortality
- 3-fold
- Decrease in hospitalizations for both cardiac and pulmonary causes
Original publication
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