Diabetes technology

Utility and Safety of Backup Insulin Regimens Generated by the Bionic Pancreas: A Randomized Study

Diabetes Technol TherPublished Randomised controlled trial

Authors' conclusion

In conclusion, a backup insulin regimen automatically generated by the BP can be safely implemented if need arises to discontinue use of the BP.

Study context

Population
Participants with T1D aged 6–83 years using the bionic pancreas, after a 13-week trial
Participants
148 vs 147
Comparison
Bionic pancreas (BP)-provided backup insulin guidance vs prestudy insulin regimen
  • BP guidancen = 148
  • Prestudy insulin regimenn = 147reference

Primary result

As reported in the abstract

Glycemic outcomes · 2-4 days
  • Glycemic outcomes with BP guidance similar to reinstituted prestudy insulin regimen
  • Both groups had higher mean glucose and lower time-in-range than while using the BP during the 13-week trial

Original publication

Utility and Safety of Backup Insulin Regimens Generated by the Bionic Pancreas: A Randomized Study. Diabetes Technol Ther. Published 22 March 2023. doi:10.1089/dia.2022.0461

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