Using Time‐Weighted Averages of Total Daily Energy Expenditure to Estimate Energy Intake During a Weight Loss Intervention
Authors' conclusion
Using a regression modeling approach, we demonstrate the DLW intake-balance method maintains accuracy during weight loss without early-phase TDEE measurements.
Study context
- Population
- Participants of a 12-month behavioral weight loss intervention (Dietary Caloric Restriction versus intermittent Fasting Trial, DRIFT)
- Comparison
- Regression models using two or three time points vs reference approach for time-weighted total daily energy expenditure (TDEE)
- Primary endpoint
- Accuracy of time-weighted TDEE and % caloric restriction estimated by regression models vs reference approach
- Follow-up
- Months 6 and 12
Methodological detailsregression modelling, bootstrap validation
- Regression modelling
- Bootstrap validation
Primary result
As reported in the abstract
Agreement of regression-model estimates with reference model
- Predictive performance of models (R 2)
- 0.911-0.982
- Limits of agreement for TDEE
- 121.1-274.5 kcal/day
- Limits of agreement for % CR
- 4.5%-10.3%
- Bias
- no significant bias
Original publication
Using Time‐Weighted Averages of Total Daily Energy Expenditure to Estimate Energy Intake During a Weight Loss Intervention. Obesity (Silver Spring). Published 28 August 2025. doi:10.
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