Osteoporosis, bone & mineral

Using Artificial Intelligence to Diagnose Osteoporotic Vertebral Fractures on Plain Radiographs

J Bone Miner ResPublished Diagnostic accuracy study

Authors' conclusion

Therefore, the AI_OVF_SH system is an efficient tool to assist radiologists and clinicians to improve the diagnosing of vertebral fractures.

Study context

Population
Plain radiographs from six community centers in Shanghai (training/internal validation) and outpatients of Shanghai Sixth People's Hospital (external validation); reference standard radiologists' Genant semiquantitative grading11,397 radiographs
Outcome
Accuracy, sensitivity, specificity, PPV and NPV for vertebral fracture diagnosis
Methodological detailsdeep-learning model development and validation, internal and external validation
  • Deep-learning model development and validation
  • Internal and external validation

Performance

As reported in the abstract

All fractures, internal validation set
Test or modelAccuracySensitivitySpecificity
AI_osteoporotic vertebral fracture (OVF)_SH97.41%84.08%97.25%

AI_osteoporotic vertebral fracture (OVF)_SH

Accuracy97.41%
Sensitivity84.08%
Specificity97.25%

Further findings

Moderate fractures, internal validation set

Sensitivity
88.55%
Specificity
99.74%

Severe fractures, internal validation set

Sensitivity
92.30%
Specificity
99.92%

All fractures, external validation set

Accuracy
96.85%
Sensitivity
83.35%
Specificity
94.70%

Moderate fractures, external validation set

Sensitivity
85.61%
Specificity
99.85%

Severe fractures, external validation set

Sensitivity
93.46%
Specificity
99.92%

Original publication

Using Artificial Intelligence to Diagnose Osteoporotic Vertebral Fractures on Plain Radiographs. J Bone Miner Res. Published 2 August 2023. doi:10.1002/jbmr.4879

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