Use of Low-Glucose Alerts and Their Impact on Continuous Glucose Monitoring Outcomes in Real-World Use of the MiniMed 780G System
Authors' conclusion
A LGAT below 60 mg/dL is generally recommended, as it is associated with increased TIR, reduced hyperglycemia, and low time in hypoglycemia.
Study context
- Population
- MiniMed 780G users with T1D across Europe, the Middle East and Africa (August 1, 2024-July 31, 2025)
- Participants
- 169,487 participants
- Exposure
- User-set low-glucose alert thresholds
- Outcome
- Glycemic targets by user-set LGAT
Methodological detailsreal-world data, anonymized
- Real-world data
- Anonymized
Main finding
As reported in the abstract
- Users who enabled LGAT
- 96%
- Users who enabled predictive LGAT
- 36%
- Hypoglycemia targets achieved, LGAT <60 mg/dL
- >82%
- Hypoglycemia targets achieved, LGAT ≥60 mg/dL
- >90%
- Time in range (TIR) 70-180 mg/dL target met, LGAT <60 mg/dL
- 70%
- Hyperglycemia targets met, LGAT <60 mg/dL
- 61%
- All glycemic targets met, LGAT <60 mg/dL
- 43%
- All glycemic targets met, LGAT >80 mg/dL
- 31%
Observational data: associations, not effects.
Original publication
Use of Low-Glucose Alerts and Their Impact on Continuous Glucose Monitoring Outcomes in Real-World Use of the MiniMed 780G System. Diabetes Technol Ther. Published 15 July 2026. doi:10.
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