Endocrine oncology

Updated Dutch 2026 pediatric differentiated thyroid carcinoma guideline: aligning with Europe

Eur J EndocrinolPublished Clinical practice guideline

Methodological detailsstructured consensus meeting, systematic comparison with European Thyroid Association (ETA) 2022 guideline
  • Structured consensus meeting
  • Systematic comparison with ETA 2022 guideline

Recommendations

As issued by the authors

  1. Most European (ETA 2022) recommendations adopted

  2. Total thyroidectomy without prior histology in Bethesda V-VI nodules with a proven BRAF mutation

  3. Expanded use of molecular diagnostics in selected nodules

  4. Referral for genetic counseling in confirmed cases

  5. Less extensive surgery and selective omission of RAI therapy in low-risk patients, based on shared decision-making

  6. Neck US follow-up limited to an initial 3-month assessment; subsequent imaging only with rising Tg or anti-Tg concentrations

Original publication

Updated Dutch 2026 pediatric differentiated thyroid carcinoma guideline: aligning with Europe. Eur J Endocrinol. Published 23 July 2026. doi:10.1093/ejendo/lvag124

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