Triglyceride-glucose index for predicting repeat revascularization and in-stent restenosis in patients with chronic coronary syndrome undergoing percutaneous coronary intervention
Main finding · Primary endpoint (repeat revascularization and ISR)Result — go to the resultHazard ratio 1.319 95% CI 1.063–1.637Authors' conclusion
An increased TyG index was associated with elevated risk for long-term PCI complications, including repeat revascularization and ISR. Our study suggested that the TyG index could be a potent predictor in evaluating the prognosis of CCS patients undergoing PCI.
Study context
- Population
- Chronic coronary syndrome (CCS) patients undergoing percutaneous coronary intervention (PCI)
- Participants
- 1,414 patients
- Exposure
- Triglyceride-glucose (TyG) index tertiles
- Outcome
- Composite of:
- PCI complications
- Including repeat revascularization
- In-stent restenosis (ISR)
- Follow-up
- Median 60 months
Main finding
As reported in the abstract
Primary endpoint:
- Repeat revascularization
- ISR
Hazard ratio
1.319
95% CI 1.063–1.637
P = 0.012
Highest tertilevs Lowest tertile
HR 1.319 (95% CI 1.063–1.637); P = 0.012
- Patients with ≥1 primary endpoint event
- 548 (38.76%)
- TyG index (continuous), adjusted HR
- 1.191; 95% CI 1.038-1.367; P = 0.013
- Linear dose-response relationship (restricted cubic splines (RCS))
- non-linear P = 0.373, P overall = 0.035
Observational data: associations, not effects.
Original publication
Triglyceride-glucose index for predicting repeat revascularization and in-stent restenosis in patients with chronic coronary syndrome undergoing percutaneous coronary intervention. Cardiovasc Diabetol. Published 2 March 2023. doi:10.
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