Triglyceride glucose index is a significant predictor of severe disturbance of consciousness and all-cause mortality in critical cerebrovascular disease patients
Authors' conclusion
The TyG index was found to be a significant predictor for severe impairment of consciousness and in-hospital death in patients with cerebrovascular disease in the ICU, and it provides some predictive value for the severity of consciousness disturbances and in-hospital mortality in cerebrovascular disease patients.
Study context
- Population
- Intensive care unit (ICU) patients with non-traumatic cerebral hemorrhage or cerebral infarction, MIMIC-IV database
- Participants
- 537 vs 872
- Exposure
- Triglyceride-glucose (TyG) index as predictor of severe consciousness disturbance and in-hospital mortality
- Cerebral hemorrhagen = 537
- Cerebral infarctionn = 872
- Outcome
- Severity of impaired consciousness and in-hospital mortality
Methodological detailsMIMIC-IV database, two cohorts
- MIMIC-IV database
- Two cohorts
Main finding
As reported in the abstract
Severe consciousness impairment and in-hospital mortality
- TyG index was a significant predictor of severity of impaired consciousness and in-hospital mortality (logistic regression)
- Risk of severe consciousness impairment and in-hospital mortality increased roughly linearly with increasing TyG index
Observational data: associations, not effects.
Original publication
Triglyceride glucose index is a significant predictor of severe disturbance of consciousness and all-cause mortality in critical cerebrovascular disease patients. Cardiovasc Diabetol. Published 29 June 2023. doi:10.
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