Triglyceride-glucose index in adolescents with type 1 diabetes mellitus
Authors' conclusion
The TyG index is a simple and non-invasive biomarker that could serve as a valuable adjunct to HbA1c monitoring in adolescents with T1DM. It may have a potential utility as a screening tool for early identification of patients at risk for developing metabolic complications such as insulin resistance and dyslipidemia.
Study context
- Population
- Adolescents with T1D (50% female), paediatric unit of the San Juan Hospital, Alicante (Spain)
- Participants
- 36 adolescents
- Outcome
- Association of TyG index with glycaemic control
Main finding
As reported in the abstract
Associations of higher TyG index
- Higher TyG index statistically associated with higher BMI, percentile and z-score
- Higher TyG index statistically associated with higher TG, HbA1c and glucose levels
- Higher TyG index statistically associated with TG/HDL, total cholesterol/HDL, TyG-BMI and TyG-waist circumference indexes
Observational data: associations, not effects.
Original publication
Triglyceride-glucose index in adolescents with type 1 diabetes mellitus. Diabetes Res Clin Pract. Published 12 February 2025. doi:10.
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