Type 1 diabetes

Psychosocial implications, acceptability and ethics of screening for paediatric type 1 diabetes: a systematic review and mixed methods evidence synthesis

DiabetologiaPublished Systematic review and mixed methods evidence synthesis

Authors' conclusion

This, the most comprehensive review of the literature to date, demonstrates that despite the emotional, cognitive and behavioural implications, thus far, screening and early detection of paediatric type 1 diabetes appears to be acceptable to parents/guardians who take part but critical evidence gaps remain.

Study context

Population
Parents and/or children aged <18 years involved in screening or early detection of paediatric T1D70 articles
Outcome
Psychosocial impact (emotional, cognitive and behavioural implications), acceptability and ethics of screening for paediatric T1D
Methodological detailsmixed methods appraisal tool and critical appraisal skills checklists for quality assessment, Searched MEDLINE, EMBASE, APA PsycInfo, ASSIA, CINAHL, Web of Science, Scopus until 25 November 2025
  • Mixed methods appraisal tool and critical appraisal skills checklists for quality assessment
  • Searched MEDLINE, EMBASE, APA PsycInfo, ASSIA, CINAHL, Web of Science, Scopus until 25 November 2025

Pooled result

As reported in the abstract

Psychosocial impact, acceptability and ethics of screening

Parents included

62,244

Children aged <18 years included

6363

Themes generated

5

Sub-themes generated

19

Further pooled results

Study quality

Met all quality criteria (high quality)
7 (10.0%)
Met 60-80% of criteria (moderate quality)
43 (61.4%)
Met <50% of criteria (low quality)
20 (28.6%)

Included article types

Qualitative
12
Quantitative
57
Mixed methods
1

Original publication

Psychosocial implications, acceptability and ethics of screening for paediatric type 1 diabetes: a systematic review and mixed methods evidence synthesis. Diabetologia. Published 1 May 2026. doi:10.1007/s00125-026-06717-2

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