Trends in comorbidities and multimorbidity among adults with recently diagnosed diabetes: United States, 1999–2023
Authors' conclusion
From 1999 to 2023, obesity, chronic lung disease, and total number of comorbidities increased among adults with new diabetes. Multimorbidity patterns increasingly encompassed both concordant and discordant conditions, potentially complicating management and worsening outcomes.
Study context
- Population
- US adults (≥20 years) with newly ascertained diabetes (diagnosed at the survey or ≤2 years prior), NHANES 1999-August 2023
- Participants
- 4,243 adults
- Exposure
- Trends across periods 1999-2006 to 2015-2023
- Outcome
- Age-adjusted prevalence of 13 comorbidities, mean comorbidity count and multimorbidity patterns
Methodological detailsnationally representative survey (NHANES), age-adjusted, three periods
- Nationally representative survey (NHANES)
- Age-adjusted
- Three periods
Main finding
As reported in the abstract
Comorbidity prevalence and count
- Obesity, 1999-2006 vs 2015-2023 (p = 0.0003)
- 58.3% to 71.0%
- Chronic lung disease (p = 0.007)
- 15.4% to 22.8%
- CKD, stable
- ∼30%
- CVD, stable
- 11.8%-14.1%
- Arthritis, common but stable
- ∼40%
- Sleep disorders, common but stable
- 29.2%-38.5%
- Dental caries, common but stable
- ∼30%
- Mean comorbidity count (p = 0.038)
- 4.25 to 4.51
- Greater overlap of concordant and discordant conditions
- p = 0.008
Observational data: associations, not effects.
Original publication
Trends in comorbidities and multimorbidity among adults with recently diagnosed diabetes: United States, 1999–2023. Diabetes Res Clin Pract. Published 27 August 2026. doi:10.
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