Trends in anti‐diabetic medication use, severe hyperglycaemia and severe hypoglycaemia among American Indian and Alaska Native Peoples, 2009–2013
Authors' conclusion
There were significant changes in the utilization of different anti-diabetic medication classes during 2009-2013 among AI/AN adults with T2D. Concurrently, there were significant reductions in severe hypoglycaemia and severe hyperglycaemia.
Study context
- Population
- AI/AN adults aged ≥18 years with T2D using Indian Health Service (IHS) or Tribal health services, fiscal years (FYs) 2009–2013
- Participants
- 39,183 adults
- Outcome
- Trends in anti-diabetic medication class use and rates of hospital admissions or emergency department (ED) visits for severe hypoglycaemia and hyperglycaemia
- Follow-up
- 2009-2013
Methodological detailsRetrospective analysis of IHS Improving Health Care Delivery Data Project
- Retrospective analysis of IHS Improving Health Care Delivery Data Project
Main finding
As reported in the abstract
- Metformin use increased
- 56.0%-60.5%
- Insulin use increased
- 31.4%-35.9%
- DPP-4i use increased
- 1.4%-9.0%
- SU use decreased significantly
- 40.3%-32.9%
- TZD use decreased significantly
- 31.6%-8.8%
- Severe hypoglycaemia declined gradually
- 1.6%-0.8%
- Severe hyperglycaemia declined gradually
- 2.0%-1.6%
Observational data: associations, not effects.
Original publication
Trends in anti‐diabetic medication use, severe hyperglycaemia and severe hypoglycaemia among American Indian and Alaska Native Peoples, 2009–2013. Diabetes Obes Metab. Published 21 October 2024. doi:10. 1111/ dom. 16021
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