Osteoporosis, bone & mineral

Trends of clinical vertebral and hip fractures following local government involvement in fracture prevention from 2015 to 2021 in Kure, Japan

Osteoporos IntPublished Population-based pre-post observational study

Authors' conclusion

Significant reductions in the incidence of both clinical vertebral and hip fractures among women were demonstrated after the launch of a comprehensive fracture prevention project supported by the local government.

Study context

Population
Residents aged ≥ 65 years in Kure, Japan, enrolled in the National Health Insurance or Senior Elderly Care System, 2015–2021
Exposure
Fracture incidence before and after the launch of municipality-supported Fracture Liaison Service (FLS) and osteoporosis awareness activities (2015 and 2021 vs 2017)
Outcome
Incidence of clinical vertebral and hip fractures
Methodological detailscommunity-wide FLS and osteoporosis awareness activities, insurance claims data, Fracture events identified using insurance claims data and ICD/treatment codes
  • Community-wide FLS and osteoporosis awareness activities
  • Insurance claims data
  • Fracture events identified using insurance claims data and ICD/treatment codes

Main finding

As reported in the abstract

Clinical vertebral fractures, incidence ratio vs 2017

Age-sex-adjusted incidence ratio

0.76

95% CI 0.70–0.83

2015

Incidence ratio

0.89

95% CI 0.82–0.96

2021

Observational data: associations, not effects.

Further findings

OutcomeEstimate
Hip fractures, incidence ratio vs 20172015 vs 2017age-sex-adjusted incidence ratio 0.87 (95% CI 0.78–0.96)
Hip fractures, incidence ratio vs 20172021 vs 2017incidence ratio 0.85 (95% CI 0.76–0.94)

Hip fractures, incidence ratio vs 2017

Incidence tended to decrease after 2017 in females but not in males

Osteoporosis prescriptions

Increase in the number of prescriptions and changes in prescribing patterns

Original publication

Trends of clinical vertebral and hip fractures following local government involvement in fracture prevention from 2015 to 2021 in Kure, Japan. Osteoporos Int. Published 19 February 2026. doi:10.1007/s00198-026-07902-0

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