Trends and burden of diabetes in patients with atrial fibrillation during 2007–2018: A Finnish nationwide cohort study
Authors' conclusion
The prevalence of diabetes has increased considerably among patients with AF between 2007 and 2018. There have been substantial improvements in the prognosis of AF patients with diabetes. However, diabetes remains a significant risk factor for IS and mortality in this patient population.
Study context
- Population
- All patients with incident atrial fibrillation (AF) in Finland, 2007–2018 (FinACAF); 50.0% female, mean age 72.7 years, mean follow-up 4.0 years
- Participants
- 229,565 patients
- Exposure
- Diabetes vs no diabetes in incident AF
- Outcome
- Temporal trends in prevalence of diabetes and its associations with ischemic stroke and mortality
- Follow-up
- 2007–2018
Main finding
As reported in the abstract
Prevalence of diabetes among patients with incident AF · 2007 to 2018
Diabetes prevalence in 2007
15.5%
Diabetes prevalence in 2018
26.3%
Observational data: associations, not effects.
Further findings
| Outcome | Adjusted IRR (95% CI) | |
|---|---|---|
| Ischemic stroke | 1.22 (1.17–1.26) | |
| Mortality | 1.32 (1.29–1.34) | |
| 0.512Adjusted incidence rate ratio (log scale) |
Ischemic stroke
- Impact of diabetes on ischemic stroke (IS) risk remained stable over the study period
Mortality
- Effect of diabetes on mortality increased slightly over the study period
Temporal trend in IS and mortality rates · 2007–2018
- IS and mortality rates decreased in patients with and without diabetes
Original publication
Trends and burden of diabetes in patients with atrial fibrillation during 2007–2018: A Finnish nationwide cohort study. Diabetes Res Clin Pract. Published 13 August 2023. doi:10.
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