Tight Glycemic Control Can Be Achieved in Adult ICU Patients Safely: Results From a 5-Year Single-Center Observational Study Using the Stochastic TARgeted (STAR) Glycemic Control Framework
Authors' conclusion
STAR provides safe, effective control for all patients in this large cohort, with minimal hypoglycemia and high nutrition rates. The protocol adapts to patients' specific needs and tolerances, encouraging STAR's adoption in other ICUs. The quality of control also enables prospective assessment of the future of GC's impact on patient outcomes.
Study context
- Population
- Adult ICU patients treated with STAR glycemic control (GC), Christchurch Hospital ICU, New Zealand, April 2019–December 20241,085 analysed
- Participants
- 1,340 patients
- Outcome
- Glycaemic control performance
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
| Group | Value | Blood glucose (BG) measurements in target band |
|---|---|---|
| STAR GC | median 124 (IQR 110–148) mg/dL | 71% |
STAR GC
Valuemedian 124 (IQR 110–148) mg/dL
Blood glucose (BG) measurements in target band71%
Observational data: associations, not effects.
Further findings
Nutrition delivery (%goal feed) and insulin rate
- Median [IQR] nutrition delivery, %goal feed
- 89.0 [17.2-100.0]
- Median [IQR] insulin rate, U/h
- 4.5 [2.0-6.0]
Per-patient consistency
- Results were consistent per-patient and improved once in the target band
Safety
- Severe hypoglycemia events (BG < 40 mg/dL)
- 3 (0.21%)
- Events unrelated to the control design
- 2
Original publication
Tight Glycemic Control Can Be Achieved in Adult ICU Patients Safely: Results From a 5-Year Single-Center Observational Study Using the STAR Glycemic Control Framework. J Diabetes Sci Technol. Published 22 January 2026. doi:10. 1177/ 19322968251412857
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