The Relationship Between Percent Time <70 mg/dL and Percent Time <54 mg/dL Measured by Continuous Glucose Monitoring
Authors' conclusion
The T<54 : T<70 ratio increases with greater T<70, and the ratio generally is higher with blinded than unblinded CGM data, with the latter appearing to be similar to AID system data.
Study context
- Population
- T1D randomized trial datasets with Dexcom continuous glucose monitoring (CGM) data9 RCTs
- Comparison
- Blinded CGM vs unblinded CGM without automated insulin delivery (AID) vs unblinded CGM with AID
- Outcome
- Relationship between CGM-measured T<70 and T<54
Methodological detailsnine T1D randomized trials, Dexcom CGM data, penalized B-spline regression
- Nine T1D randomized trials
- Dexcom CGM data
- Penalized B-spline regression
Pooled result
As reported in the abstract
Predicted T<54 when T<70 was 4%
P < 0.001 comparing blinded versus unblinded and AID
- T<54 : T<70 ratio, blinded data: from T<70 <1% to T<70 ≥7%
- 19% to 44%
- T<54 : T<70 ratio, unblinded data: from T<70 <1% to T<70 ≥7%
- 15% to 42%
Original publication
The Relationship Between Percent Time <70 mg/dL and Percent Time <54 mg/dL Measured by Continuous Glucose Monitoring. Diabetes Technol Ther. Published 10 January 2023. doi:10.
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