Obesity

The neural pathways of change: an fMRI study of the effects of behavioral change suggestions on value-based dietary decision-making

Int J Obes (Lond)Published Mechanistic study

Authors' conclusion

These findings indicate that shifting between changing and sustaining unhealthy eating habits biases food valuation and its encoding in neural pathways linked to valuation, cognitive control, and craving as a function of weight status.

Study context

Population
Participants with varying BMI and food addiction-like symptoms who underwent a motivational interviewing session
Participants
85 participants
Comparison
Listening to own change talk vs sustain talk statements during food choice
Outcome
Food choices
Follow-up
One week after motivational interviewing session
Methodological detailsfMRI, within-participant change talk vs sustain talk, pre-registered
  • fMRI
  • Within-participant change talk vs sustain talk
  • Pre-registered

Main finding

As reported in the abstract

  • Food choices were healthier after listening to change talk, and more based on taste after sustain talk
  • Effect stronger with BMI ≥ 25 kg/m², particularly with more food addiction-like symptoms

Further findings

Neural responses (fMRI) · at time of food choice

BMI ≥ 25 kg/m²: stronger functional connectivity between ventromedial and dorsolateral prefrontal cortex after change vs sustain talk
BMI < 30 kg/m²: stronger neural craving responses during food choice after sustain talk
After change talk, BMI < 30 kg/m²: higher BMI linked to stronger neural craving responses during healthy food wanting and lower during tasty food wanting

Original publication

The neural pathways of change: an fMRI study of the effects of behavioral change suggestions on value-based dietary decision-making. Int J Obes (Lond). Published 10 February 2026. doi:10.1038/s41366-026-02018-1

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