Osteoporosis, bone & mineral

The Impact of Whole Egg Consumption on Bone Accrual in Healthy Children: A Randomized Controlled Trial

J Bone Miner ResPublished Randomised controlled trial

Authors' conclusion

Whole eggs provide important nutritional benefits for children, but the bone responses to consumption of 8-10 eggs/wk over a period of 9 months in children entering the early stages of puberty were small.

Study context

Population
Male and female children aged 9–13 years of different ancestries
Comparison
Foods with whole eggs vs foods with milk or gelatin for 9 months
Primary endpoint
Measures of bone strength: TBLH and lumbar spine bone mineral content (BMC) and areal bone mineral density (aBMD) (DXA, HAZ-adjusted Z-scores); mid-tibia cortical bone measures (pQCT)
Follow-up
9 months
Methodological detailsdouble-blind
  • Double-blind

Primary result

As reported in the abstract

Bone outcomes
  • No significant intervention effects for any bone outcomes

Further findings

OutcomeP value
Spine BMCHAZ Z-score increase · 9 monthsEgg vs Gelatin · increase in egg vs gelatin approached significanceP = 0.07

Total body less head (TBLH) aBMDHAZ Z-score · 9 months

Significant time effect: all groups decreased over 9 months
P < 0.03

Tibia cortical bone outcomes · 9 months

Most increased over time; changes did not differ across intervention groups
all p < 0.02

Original publication

The Impact of Whole Egg Consumption on Bone Accrual in Healthy Children: A Randomized Controlled Trial. J Bone Miner Res. Published 1 December 2023. doi:10.1002/jbmr.4929

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