The impact of the COVID-19 pandemic and associated disruptions in health-care provision on clinical outcomes in people with diabetes: a systematic review
Authors' conclusion
Where reported, the impact was most pronounced for females, younger people, and racial and ethnic minority groups.
Study context
- Population
- People with diabetes; MEDLINE and OVID, Jan 1, 2020, to June 7, 2023
- Participants
- n>1,000,000 people138 studies
- Comparison
- Pandemic vs prepandemic periods
- Outcome
- Clinical outcomes in people with diabetes
Methodological detailsAll but five studies were judged to be at some risk of bias
- All but five studies were judged to be at some risk of bias
Pooled result
As reported in the abstract
Clinical outcomes
- All-cause mortality: consistent increases
- 6 studies
- Diabetes-related mortality: consistent increases
- 13 studies
- Sight loss: increases in most studies
- 6 studies
- DKA in adult and mixed samples: generally no difference in frequency or severity; in children and adolescents most studies showed increases, some due to new-onset diabetes
- 69 studies
- Hospital admissions: decreases in adults; increases in diabetes-related paediatric ICU admissions
- 35 studies
- DFU presentations: equivocal
- 9 studies
- ED admissions: equivocal
- 9 studies
- Overall amputation rates: equivocal
- 20 studies
Original publication
The impact of the COVID-19 pandemic and associated disruptions in health-care provision on clinical outcomes in people with diabetes: a systematic review. Lancet Diabetes Endocrinol. Published February 2024. doi:10. 1016/ s2213-8587(23)00351-0
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