Diabetes complications

The impact of the COVID-19 pandemic and associated disruptions in health-care provision on clinical outcomes in people with diabetes: a systematic review

Lancet Diabetes EndocrinolPublished Systematic review

Authors' conclusion

Where reported, the impact was most pronounced for females, younger people, and racial and ethnic minority groups.

Study context

Population
People with diabetes; MEDLINE and OVID, Jan 1, 2020, to June 7, 2023
Participants
n>1,000,000 people138 studies
Comparison
Pandemic vs prepandemic periods
Outcome
Clinical outcomes in people with diabetes
Methodological detailsAll but five studies were judged to be at some risk of bias
  • All but five studies were judged to be at some risk of bias

Pooled result

As reported in the abstract

Clinical outcomes
All-cause mortality: consistent increases
6 studies
Diabetes-related mortality: consistent increases
13 studies
Sight loss: increases in most studies
6 studies
DKA in adult and mixed samples: generally no difference in frequency or severity; in children and adolescents most studies showed increases, some due to new-onset diabetes
69 studies
Hospital admissions: decreases in adults; increases in diabetes-related paediatric ICU admissions
35 studies
DFU presentations: equivocal
9 studies
ED admissions: equivocal
9 studies
Overall amputation rates: equivocal
20 studies

Original publication

The impact of the COVID-19 pandemic and associated disruptions in health-care provision on clinical outcomes in people with diabetes: a systematic review. Lancet Diabetes Endocrinol. Published February 2024. doi:10.1016/s2213-8587(23)00351-0

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