Diabetes complications

The impact of residual diabetic toe osteomyelitis at the conservative surgical resection margins on prognosis

Diabet MedPublished Retrospective cohort study

Main finding · Wound healing timeResult — go to the resultHazard ratio 1.195 95% CI 0.668–2.136

Authors' conclusion

The residual osteomyelitis in diabetic toe osteomyelitis post-conservative surgery does not impact the wound healing.

Study context

Population
Patients with diabetic toe osteomyelitis (histopathology-diagnosed) who underwent conservative surgery
Participants
67 patients
Exposure
Positive vs negative bone margins after conservative surgery
  • Positive bone marginsn = 48
  • Negative bone marginsn = 19reference
Outcome
Wound healing time
Follow-up
16-week after discharge

Main finding

As reported in the abstract

Hazard ratio

1.195

95% CI 0.668–2.136

P = 0.549

By group

Positive bone marginsvs Negative bone margins
HR 1.195 (95% CI 0.668–2.136); P = 0.549

Observational data: associations, not effects.

Further findings

Wound healing rate

P = 0.93

Inpatient days

P = 0.385

Duration of antibiotics

P = 0.272

Ankle-brachial index as factor influencing wound healing

HR
5.399 (95% CI 1.145-25.455; p = 0.033)
  • Cox regression

Original publication

The impact of residual diabetic toe osteomyelitis at the conservative surgical resection margins on prognosis. Diabet Med. Published 19 December 2024. doi:10.1111/dme.15502

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