Gestational diabetes & diabetes in pregnancy
The impact of obesity on pregnancy outcomes in women with type 1 and type 2 diabetes across the NSW population: A retrospective cohort study
Main finding · Adverse perinatal outcomes, T1D vs T2DResult — go to the resultAdjusted odds ratio >1Authors' conclusion
Women with T1D had higher odds of adverse perinatal outcomes compared to those with T2D. Obesity increased risk in women with T2D, but not T1D, raising the possibility that targeted weight interventions in those with T2D may reduce the risk of adverse perinatal outcomes.
Study context
- Population
- Singleton births of nulliparous mothers with T1D and T2D, 2016–2020, New South Wales, Australia
- Participants
- 568 vs 910
- Exposure
- T1D vs T2D, and impact of concurrent obesity
- T1Dn = 568
- T2Dn = 910reference
- Outcome
- Adverse perinatal outcomes by diabetes type and impact of concurrent obesity
Methodological detailspopulation-based, stepwise adjustment for maternal covariates
- Population-based
- Stepwise adjustment for maternal covariates
Main finding
Adverse perinatal outcomes, T1D vs T2D
Adjusted odds ratio
>1
P < 0.05
As reported in the abstract
Observational data: associations, not effects.
Further findings
Obesity vs no obesity in T2D: adverse outcomes
- Gestational hypertension, aOR (CI), p
- 5.88 (1.38-25.15), p = 0.02
- Postpartum haemorrhage, aOR (CI), p
- 1.95 (1.18-3.23), p < 0.01
- Caesarean section, aOR (CI), p
- 2.29 (1.59-3.30), p < 0.01
- Large-for-gestational age (LGA), aOR (CI), p
- 1.82 (1.13-2.93), p = 0.01
- Neonatal hypoglycaemia, aOR (CI), p
- 1.53 (1.02-2.30), p = 0.04
- Neonatal resuscitation, aOR (CI), p
- 1.81 (1.19-2.76), p < 0.01
- Obesity increased odds in T2D but not T1D
Baseline characteristics
- Women with T2D were older, had higher BMI, more pre-existing hypertension and smoking, and more socioeconomic disadvantage
- P < 0.01
Original publication
The impact of obesity on pregnancy outcomes in women with type 1 and type 2 diabetes across the NSW population: A retrospective cohort study. Diabet Med. Published 3 December 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →