Gestational diabetes & diabetes in pregnancy
The Effectiveness of Superbolus on Postprandial Blood Glucose Management of Pregnant Women With Type 1 Diabetes
Authors' conclusion
Superbolus was effective in avoiding after-meal glucose peaks, increased postprandial glucose time in target, without late hypoglycemia occurrence. It represents a valid option for the treatment of pregnant women with type 1 diabetes using insulin pump.
Study context
- Population
- Consecutive pregnant women with T1D on insulin pump therapy, advised to use superbolus for breakfast; mean age 34.3 ± 5.5 years, pregestational BMI 23.7 ± 4.7 kg/m², HbA1c in pregnancy 6.1 ± 0.6%CGM data
- Participants
- 21 women
- Exposure
- Breakfast glucose control after vs before superbolus use
- Outcome
- Glucose 1 hour after breakfast
- Follow-up
- 1 hour after breakfast
Methodological detailsbefore-after comparison
- Before-after comparison
Main finding
As reported in the abstract
P = 0.01
Observational data: associations, not effects.
Further findings
| Outcome | After superbolus | Before superbolus | P value |
|---|---|---|---|
| Number of late hypoglycemic episodesReduced with superbolus | 1 [0-2] | 3 [1-5] | P < 0.0001 |
- TIR for the after-breakfast period · improved with superbolus
- P = 0.001
TIR for the after-breakfast period
- Superbolus improved the TIR for the after-breakfast period
Original publication
The Effectiveness of Superbolus on Postprandial Blood Glucose Management of Pregnant Women With Type 1 Diabetes. J Diabetes Sci Technol. Published 5 July 2022. doi:10.
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