Pituitary & hypothalamus

The effect of mindfulness therapy in acromegaly, a pilot study

Clin Endocrinol (Oxf)Published Randomised controlled trial

Authors' conclusion

We have demonstrated for the first time the value of a mindfulness program in patients with acromegaly, analysing possible effects and advantages, and clarifying the usefulness of a specific protocol for the disease.

Study context

Population
Patients with acromegaly, 2 centres (Barcelona-BCN and Bergamo-BG), 30 per centre30 per centre
Participants
60 patients
Comparison
8-week face-to-face group mindfulness program vs normal clinical routine
Methodological detailsmulticentre, international, pilot
  • Multicentre
  • International
  • Pilot

Primary result

As reported in the abstract

Changes in QoL, mood, pain, sleep, self-compassion, life satisfaction, blood pressure and heart rate after program
BCN intervention: increase in night-time hours in bed after program
p = 0.05
Both centres: trend to reduced time to start sleeping
p = 0.06 BCN, p = 0.07 BG
BCN: intervention reduced pain score vs control
p = .02
BCN: improvement in self-compassion
p = .04
Both centres: heart rate decreased significantly in intervention during a single 2-hour session, at first and last session
BCN p = .013 and p = .009; BG < 0.001 and p = .04
BG training effect: heart rate fell more in last session than first
p = 002

Original publication

The effect of mindfulness therapy in acromegaly, a pilot study. Clin Endocrinol (Oxf). Published 28 November 2022. doi:10.1111/cen.14844

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