The Clinical Utility of Individual Iodine Status Measures in Infants With Abnormal Thyroid Function: A Systematic Review
Authors' conclusion
No single method reliably assesses iodine status in individual infants.
Study context
- Population
- Infants under 2 years of age with abnormal thyroid function31 studies
- Outcome
- Methods used to assess individual iodine status and their clinical utility in relation to thyroid dysfunction
Methodological detailsPRISMA guidelines, protocol registered on PROSPERO, five databases and grey literature, backward and forward citation searching, dual independent screening, extraction and appraisal
- PRISMA guidelines
- Protocol registered on PROSPERO
- Five databases and grey literature
- Backward and forward citation searching
- Dual independent screening, extraction and appraisal
Pooled result
As reported in the abstract
Individual iodine status measures
Urinary iodine concentration (UIC) was the most used method, with significant heterogeneity
26 studies
Original publication
The Clinical Utility of Individual Iodine Status Measures in Infants With Abnormal Thyroid Function: A Systematic Review. Clin Endocrinol (Oxf). Published 30 September 2026. doi:10.
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