The bidirectional association between diabetes and long-COVID-19 – A systematic review
Authors' conclusion
COVID-19 survivors may be at increased risk for new-onset diabetes, but whether pre-existing diabetes is also a risk factor for PASC remains unclear.
Study context
- Population
- Longitudinal studies of PASC (sequelae >4 weeks after infection) in people with vs without diabetes, and of new-onset diabetes in people with vs without COVID-19 (≥4 weeks follow-up); search through August 8, 202239 studies
- Comparison
- Diabetes vs no diabetes; COVID-19 vs no COVID-19
- Outcome
- Diabetes as risk factor for PASC (25 studies)
Methodological detailsPRISMA guidelines, longitudinal studies, English-language studies, 5,532 studies screened
- PRISMA guidelines
- Longitudinal studies
- English-language studies
- 5,532 studies screened
Pooled result
As reported in the abstract
Studies identifying diabetes as a significant risk factor for PASC
44 %
n = 11
Increased relative risk range in those studies
7 % to 342 %
Studies not identifying diabetes as a significant risk factor
56 %
n = 14
Further pooled results
COVID-19 vs no COVID and new-onset diabetes (14 studies)
- Studies reporting COVID-19 significantly associated with new-onset diabetes
- 12 (86 %)
- Increased risk range
- 11 % to 276 %
Original publication
The bidirectional association between diabetes and long-COVID-19 – A systematic review. Diabetes Res Clin Pract. Published 7 December 2022. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →