Type 2 & other diabetes

The temporal interplay between physical activity, emotional well-being, and health-related quality of life in individuals with recently diagnosed type 2 diabetes mellitus: a cross-lagged panel analysis

Diabetes Res Clin PractPublished Prospective cohort study

Authors' conclusion

HRQoL and EWB predicted subsequent MVPA, whereas MVPA showed limited and inconsistent effects on later HRQoL or EWB.

Study context

Population
Adults recently diagnosed with T2D
Participants
972 participants
Outcome
Bidirectional associations between accelerometry-measured MVPA, health-related quality of life (HRQoL) (SF-12 PCS, MCS) and emotional well-being (WHO-5)
Follow-up
Baseline, 24 and 48 months
Methodological detailsthree-wave cross-lagged panel model, adjusted for age and sex
  • Three-wave cross-lagged panel model
  • Adjusted for age and sex

Main finding

As reported in the abstract

Baseline PCS predicted moderate to vigorous physical activity (MVPA) at 24 months
β = 0.124, p < 0.001
PCS at 24 months predicted MVPA at 48 months
β = 0.146, p < 0.001
Baseline MCS predicted MVPA at 24 months
β = 0.116, p = 0.001
Baseline MCS did not predict MVPA at 48 months
β = −0.016, p = 0.653
Baseline emotional well-being (EWB) predicted MVPA at 24 months
β = 0.080, p = 0.023
Baseline EWB did not predict MVPA at 48 months
β = 0.068, p = 0.058
Baseline MVPA did not predict PCS at 24 months
β = 0.038, p = 0.184
MVPA at 24 months predicted PCS at 48 months
β = 0.065, p = 0.024

Observational data: associations, not effects.

Original publication

The temporal interplay between physical activity, emotional well-being, and health-related quality of life in individuals with recently diagnosed type 2 diabetes mellitus: a cross-lagged panel analysis. Diabetes Res Clin Pract. Published 23 February 2026. doi:10.1016/j.diabres.2026.113185

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