Diabetes technology

A systematic review on the impact of commercially available hybrid closed loop systems on psychological outcomes in youths with type 1 diabetes and their parents

Diabet MedPublished Systematic review

Authors' conclusion

Evidence confirms the importance of evaluating the psychosocial needs of youths with diabetes and their families when starting HCL systems and during follow-up, and to set realistic expectations of what can be achieved along with awareness of the limitations of the systems, and educate and motivate families to overcome barriers.

Study context

Population
Youths with T1D and their parents31 studies
Participants
20 vs 11
Comparison
Commercially available hybrid closed loop (HCL) systems
  • First-generation HCLn = 20
  • Second-generation HCLn = 11
Outcome
Psychological outcomes
Methodological detailsPICOS framework, GRADE evidence assessment, studies published in last 10 years, 215 studies identified after duplicate removal
  • PICOS framework
  • GRADE evidence assessment
  • Studies published in last 10 years
  • 215 studies identified after duplicate removal

Pooled result

As reported in the abstract

  • Per studies with moderate- to high-level quality of evidence, HCL systems led to better or, in some studies, unchanged diabetes distress and burden, fear of hypoglycemia, quality of life and satisfaction
  • Sleep quality perceived as improved, but not confirmed in studies using actigraphy
  • Semi-structured interviews: positive experience and attitude towards HCL, felt easy to use and apt to achieve glycemic targets

Original publication

A systematic review on the impact of commercially available hybrid closed loop systems on psychological outcomes in youths with type 1 diabetes and their parents. Diabet Med. Published 17 April 2023. doi:10.1111/dme.15099

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