Sustained Reduction of Subclinical Inflammation in the Years After Breastfeeding
Authors' conclusion
Sustained reduction of subclinical inflammation may contribute to the cardioprotective effect of lactation in women.
Study context
- Population
- Postpartum women with serial cardiometabolic characterization at 1, 3 and 5 years post partum
- Participants
- 328 women
- Exposure
- Exclusive breastfeeding <3 months vs 3–6 months vs ≥6 months
- <3 monthsn = 107
- 3–6 monthsn = 101
- ≥6 monthsn = 120
- Outcome
- CV risk factors by duration of exclusive breastfeeding
- Follow-up
- 1, 3 and 5 years post partum
Main finding
As reported in the abstract
Metabolic syndrome prevalence · 5 years post partum
P = 0.02
Observational data: associations, not effects.
Further findings
CRP (covariate-adjusted) · 3 and 5 years post partum
- Higher CRP with <3 months exclusive breastfeeding at 3 years
- P = 0.04
- Higher CRP with <3 months exclusive breastfeeding at 5 years
- P = 0.01
- CRP remained higher over time with <3 months vs peers, 1 to 5 years (GEE, adjusted incl. time-dependent BMI)
- P = 0.03
Original publication
Sustained Reduction of Subclinical Inflammation in the Years After Breastfeeding. J Clin Endocrinol Metab. Published 2 November 2024. doi:10.
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