Obesity

Socio‐demographic and clinical factors associated with the receipt of anti‐obesity medication prescriptions and metabolic and bariatric surgery among eligible all of Us participants

Diabetes Obes MetabPublished Cross-sectional study

Authors' conclusion

Disparities in obesity treatment exist. Male sex, older age, lower income and lower BMI were associated with lower odds of treatment, while dyslipidaemia and obstructive sleep apnoea were associated with higher odds.

Study context

Population
Patients with obesity in the All of Us (AoU) Research (v.8) data, 2017–2023Anti-obesity medications (AOM) analysis
Participants
183,424 patients
Exposure
Socio-demographic and clinical factors associated with receipt of AOM prescriptions and metabolic and bariatric surgery (MBS)
Outcome
Receipt of AOM prescriptions and MBS

Main finding

As reported in the abstract

2017–2023
Adjusted odds ratio (95% CI)
Manvs Womanreceipt of AOM; lower odds with Man
0.62(0.59–0.65)
Medicarevs Privatereceipt of AOM; insurance
0.78(0.72–0.84)
Retireevs Employedreceipt of AOM
0.70(0.66–0.75)
High schoolvs Collegereceipt of AOM; education
0.85(0.80–0.90)
Singlevs MarriedMBS
0.84(0.74–0.96)
Retiredvs EmployedMBS
0.63(0.49–0.80)
BMI 35- < 40vs BMI ≥45MBS
0.13(0.11–0.15)
Received an AOM prescription (of 183 424 patients)
6.6%
Underwent MBS (of 93 146 patients)
1.8%

Observational data: associations, not effects.

Original publication

Socio‐demographic and clinical factors associated with the receipt of anti‐obesity medication prescriptions and metabolic and bariatric surgery among eligible all of Us participants. Diabetes Obes Metab. Published 19 June 2025. doi:10.1111/dom.16544

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