Siesta behavior and genetics interact to influence obesity risk
Authors' conclusion
Considering the ongoing debate regarding whether siesta is beneficial or detrimental, our findings suggest that individual genetic predisposition to siesta might influence the association between siesta and health.
Study context
- Population
- Mediterranean population (ONTIME study), in whom siesta is deeply rootedONTIME study
- Participants
- 1,278 participants
- Exposure
- Siesta vs no siesta, by genetic propensity for siesta
- Outcome
- Interactions between obesity, siesta behavior and genetic propensity for siesta (obesity grade)
Methodological detailsSiesta-PGS applied; logistic regression
- Siesta-PGS applied; logistic regression
Main finding
As reported in the abstract
- Usually took siesta
- 42.4%
- Higher genetic predisposition linked to taking siesta more frequently: OR
- 1.17 (1.03-1.32); p = 0.015 (95% CI)
- Among high genetic propensity for siesta, usual siesta takers had lower odds of obesity vs non-takers
- p = 0.038
Observational data: associations, not effects.
Further findings
Dietary habits by genetic propensity for siesta
- Higher genetic propensity for siesta: poorer dietary habits
- P < 0.05
Weight-loss success (high genetic propensity subgroup)
- Among high genetic propensity for siesta, usual siesta takers had higher odds of weight-loss success vs non-takers
- P = 0.007
- Exploratory analysis
Original publication
Siesta behavior and genetics interact to influence obesity risk. Obesity (Silver Spring). Published 23 December 2024. doi:10.
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