Obesity

Sex-dependent associations of childhood maltreatment with obesity-related traits: results from the German National Cohort (NAKO)

Int J Obes (Lond)Published Population-based cohort study

Authors' conclusion

Associations of CM exposure with adult anthropometric and body fat markers are stronger in females compared to males.

Study context

Population
Adults in the German National Cohort (NAKO); Childhood Maltreatment (CM) assessed with the Childhood Trauma Screener (CTS)74,596 female
Participants
151,143 adults
Exposure
Childhood maltreatment exposure vs no exposure, by sex
Outcome
Associations of CM with obesity-related traits by sex
Methodological detailssex-stratified analyses
  • Sex-stratified analyses

Main finding

As reported in the abstract

≥3 CM subtypes vs UnexposedOdds ratio (95% CI)
Females; obesity (BMI ≥ 30 kg/m²)
1.56(1.43–1.71)
Females; high WC (WC ≥ 88 cm)
1.39(1.29–1.50)
Males; obesity
1.51(1.32–1.72)
Males; high WC (WC ≥ 102 cm)
1.31(1.18–1.44)

Observational data: associations, not effects.

Further findings

CM subtypes

Physical and emotional abuse showed the strongest average associations and were associated with the most outcomes

Original publication

Sex-dependent associations of childhood maltreatment with obesity-related traits: results from the German National Cohort (NAKO). Int J Obes (Lond). Published 6 February 2026. doi:10.1038/s41366-025-01914-2

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