Selective Collection of Exhaled Breath Condensate for Noninvasive Screening of Breath Glucose
Authors' conclusion
Temperature-based selective EBC collection allows EBC glucose measurement and is a promising sampling method to distinguish patients with and without diabetes.
Study context
- Population
- Participants with T2D and normoglycemic participants undergoing OGTT
- Comparison
- Temperature-based selective (alveolar) exhaled breath condensate (EBC) collection vs overall EBC; T2D vs normoglycemic participants
- Outcome
- EBC glucose with selective alveolar collection
Methodological detailsPilot use during OGTT, Custom EBC collection device with temperature-based algorithm to selectively condense alveolar air
- Pilot use during OGTT
- Custom EBC collection device with temperature-based algorithm to selectively condense alveolar air
Main finding
As reported in the abstract
- Selective alveolar capture gave slightly higher and less variable glucose concentrations than overall EBC
- Significantly higher blood plasma-EBC glucose ratios in T2D than normoglycemic participants
Original publication
Selective Collection of Exhaled Breath Condensate for Noninvasive Screening of Breath Glucose. J Diabetes Sci Technol. Published 4 July 2023. doi:10.
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