Osteoporosis, bone & mineral

Rural–urban differences in osteoporosis and sarcopenia prevalence among Gambian older adults: a pilot study

J Bone Miner ResPublished Cross-sectional study

Authors' conclusion

Our findings highlight that osteoporosis and sarcopenia are highly prevalent in older Gambian adults, with differences in rural-urban prevalence influenced by sex.

Study context

Population
Gambian adults aged ≥55 yr from rural and urban communities; DXA (TH, FN, LS) and peripheral QCT (pQCT) (radius, tibia)
Participants
209 vs 101
Exposure
Rural vs urban Gambian older adults
  • Ruraln = 209
  • Urbann = 101
Outcome
Prevalence of osteoporosis (NHANES III, T-score < −2.5) and sarcopenia (EWGSOP2 ALM and HGS); rural-urban differences in DXA and pQCT outcomes
Methodological detailspilot study
  • Pilot study

Main finding

As reported in the abstract

Osteoporosis at FN or TH

Urban men vs rural men

20% vs rural 10%

Rural women vs urban women

45% vs urban 31%

Observational data: associations, not effects.

Further findings

LS T-score < −2.5, rural vs urban

Men, rural vs urban
27% vs 14%
Women, rural vs urban
61% vs 35%

Sarcopenia, rural vs urban

Men, rural vs urban
30% vs. 18%
Women, rural vs urban
18% vs 15%

DXA and pQCT outcomes, adjusted for age and fat mass index (FMI)

Urban Gambians had lower BMC but greater bone area (BA) at the FN and TH, while areal BMD (aBMD) differed little
Urban men had lower adjusted tibial cortical volumetric BMD (vBMD) but greater tibial diaphyseal and radial epiphyseal cross-sectional area (CSA)
After adjustment, urban women had greater radial CSA and estimated strength
  • Adjusted for age and FMI

Original publication

Rural–urban differences in osteoporosis and sarcopenia prevalence among Gambian older adults: a pilot study. J Bone Miner Res. Published 22 September 2025. doi:10.1093/jbmr/zjaf130

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