Type 2 & other diabetes

Risk prediction of bladder cancer among person with diabetes: A derivation and validation study

Diabet MedPublished Derivation and validation study of a clinical risk score

Performance · Prevalence of bladder cancer by risk category (derivation cohort)Result — go to the resultFold increased prevalence 3.26 95% CI 1.65–6.44

Authors' conclusion

The risk prediction algorithm may inform urgency of cystoscopy appointments, thus allowing a more efficient use of resources and contributing to early detection of BCa among people planned to be referred.

Study context

Population
People with diabetes who received cystoscopy, large database in the Chinese population (2009–2018)123 with BCa
Participants
5,905 people
Comparison
High-risk vs average-risk category
Outcome
Prevalence of bladder cancer by risk category (derivation cohort)
Methodological detailsrandom sampling of 70% for derivation cohort, risk score from adjusted odds ratios
  • Random sampling of 70% for derivation cohort
  • Risk score from adjusted odds ratios

Performance

As reported in the abstract

Fold increased prevalence

3.26

95% CI 1.65–6.44

P = 0.025

By group

Concordance (c-) statistic
0.72

Further findings

OutcomeDerivationValidation
Prevalence of bladder cancer by cohort2.2% · n = 41741.8% · n = 1731

Original publication

Risk prediction of bladder cancer among person with diabetes: A derivation and validation study. Diabet Med. Published 23 August 2023. doi:10.1111/dme.15199

Composed by AI from the published abstract and checked against it. How Briefs are made →

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