Type 2 & other diabetes

Risk of healthcare visits from influenza in subjects with diabetes and impacts of early vaccination

BMJ Open Diabetes Res CarePublished Retrospective cohort study

Authors' conclusion

The risk for influenza-related healthcare utilization was 3.7-fold higher if patients had diabetes during 2013-2016 influenza seasons. Early immunization provides a significant benefit to adults irrespective of a diabetes diagnosis. All adults, but particularly patients with diabetes, should be encouraged to get the influenza vaccine at the start of the influenza season.

Study context

Population
Adults ≥18 years with ≥2 records, two Louisiana healthcare providers, January 2012–December 20171,117,263 records
Exposure
Diabetes vs no diabetes; early vs later influenza vaccination
Outcome
Influenza-related diagnosis during inpatient or ER visits and risk reduction with timing of immunization
Follow-up
2013-2016 influenza seasons
Methodological detailselectronic medical records, two Louisiana healthcare providers
  • Electronic medical records
  • Two Louisiana healthcare providers

Main finding

As reported in the abstract

Influenza-related IP or ER visits

Fold more frequent

5.6

unadjusted

Fold more frequent

3.7

adjusted for demographics

Influenza-related inpatient (IP) or emergency room (ER) visits, events per person (all subjects)
0.0122-0.0169
Risk reduction with early vs later vaccination, diabetes
66%
Risk reduction with early vs later vaccination, no diabetes
67%

Observational data: associations, not effects.

Further findings

Older age and female sex associated with higher influenza incidence, but no significant change in risk reduction from vaccination

Original publication

Risk of healthcare visits from influenza in subjects with diabetes and impacts of early vaccination. BMJ Open Diabetes Res Care. Published 6 August 2024. doi:10.1136/bmjdrc-2023-003841

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