Risk of healthcare visits from influenza in subjects with diabetes and impacts of early vaccination
Authors' conclusion
The risk for influenza-related healthcare utilization was 3.7-fold higher if patients had diabetes during 2013-2016 influenza seasons. Early immunization provides a significant benefit to adults irrespective of a diabetes diagnosis. All adults, but particularly patients with diabetes, should be encouraged to get the influenza vaccine at the start of the influenza season.
Study context
- Population
- Adults ≥18 years with ≥2 records, two Louisiana healthcare providers, January 2012–December 20171,117,263 records
- Exposure
- Diabetes vs no diabetes; early vs later influenza vaccination
- Outcome
- Influenza-related diagnosis during inpatient or ER visits and risk reduction with timing of immunization
- Follow-up
- 2013-2016 influenza seasons
Methodological detailselectronic medical records, two Louisiana healthcare providers
- Electronic medical records
- Two Louisiana healthcare providers
Main finding
As reported in the abstract
Influenza-related IP or ER visits
Fold more frequent
5.6
unadjusted
Fold more frequent
3.7
adjusted for demographics
- Influenza-related inpatient (IP) or emergency room (ER) visits, events per person (all subjects)
- 0.0122-0.0169
- Risk reduction with early vs later vaccination, diabetes
- 66%
- Risk reduction with early vs later vaccination, no diabetes
- 67%
Observational data: associations, not effects.
Further findings
- Older age and female sex associated with higher influenza incidence, but no significant change in risk reduction from vaccination
Original publication
Risk of healthcare visits from influenza in subjects with diabetes and impacts of early vaccination. BMJ Open Diabetes Res Care. Published 6 August 2024. doi:10. 1136/ bmjdrc-2023-003841
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