Risk factors for peripheral arterial disease in type 2 diabetes mellitus patients: A systematic review and meta-analysis
Authors' conclusion
Age ≥ 70 years old, diabetes duration ≥ 5 years, CAD history, hypertension, and increased LDL are significant risk factors for PAD in the T2DM population.
Study context
- Population
- T2D populations
- Participants
- 73,834 samples10 studies
- Comparison
- Risk factors for peripheral arterial disease (PAD) in T2D
- Outcome
- Pooled effect estimates of risk factors of peripheral arterial disease (PAD)
Methodological detailsSearch of PubMed/MEDLINE, ProQuest and EMBASE; risk of bias by Newcastle-Ottawa Scale; all studies low risk of bias
- Search of PubMed/MEDLINE, ProQuest and EMBASE; risk of bias by Newcastle-Ottawa Scale; all studies low risk of bias
Pooled result
As reported in the abstract
Association with PAD in T2D
- Age ≥ 70 years: OR
- 3.44 (95 % CI 2.11, 5.62)
- Diabetes duration ≥ 5 years: OR
- 1.81 (95 % CI 1.24, 2.64)
- Coronary artery disease (CAD) history: OR
- 1.55 (95 % CI 1.30, 1.83)
- Hypertension: OR
- 1.43 (95 % CI 1.10, 1.86)
- Increased LDL: OR
- 2.51 (95 % CI 1.38, 4.56)
Original publication
Risk factors for peripheral arterial disease in type 2 diabetes mellitus patients: A systematic review and meta-analysis. Diabetes Res Clin Pract. Published 10 April 2025. doi:10.
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