Risk factors for Charcot foot development in individuals with diabetes mellitus
Authors' conclusion
In the most extensive study on Charcot foot to date, we identified distinctive and common risk factors associated with the development of Charcot foot in individuals with type 1 diabetes and type 2 diabetes.
Study context
- Population
- Individuals with DM (T1D and T2D) in nationwide registries, 2001–2016
- Participants
- 3,397 vs 27,662
- Exposure
- Charcot foot vs no Charcot foot, among individuals with DM
- Charcot footn = 3,397
- Controlsn = 27,662reference
- Outcome
- Risk factors for Charcot foot (logistic regression)
Methodological detailsregister-based, nationwide, matched by diabetes type and similar diabetes duration
- Register-based
- Nationwide
- Matched by diabetes type and similar diabetes duration
Main finding
As reported in the abstract
Risk factors for Charcot foot
- HbA1c, duration of diabetes, micro- and macroalbuminuria, retinopathy and atherosclerosis (general and peripheral) identified as risk factors for Charcot foot in T1D and T2D
Observational data: associations, not effects.
Original publication
Risk factors for Charcot foot development in individuals with diabetes mellitus. Diabetologia. Published 13 September 2024. doi:10. 1007/ s00125-024-06271-9
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