Risk Factors and Consequences of Lapses in Proliferative Diabetic Retinopathy Care in a National Cohort
Authors' conclusion
Prolonged lapses in PDR care are common, disproportionately affect vulnerable groups, and are associated with persistent vision loss.
Study context
- Population
- Adults with proliferative diabetic retinopathy (PDR) and ≥6 months of follow-up in the Sight Outcomes Research Collaborative (2008–2023)
- Participants
- 15,211 adults
- Outcome
- Prevalence, risk factors and visual outcomes of occurrence and duration of lapses in PDR care
Methodological detailsnational, multivariable regression
- National
- Multivariable regression
Main finding
As reported in the abstract
Lapse in PDR care
Experienced a lapse in care
71.8%
Lapses lasting >24 months
14.2%
Observational data: associations, not effects.
Further findings
Risk factors for lapse occurrence
- Lapses more common among non-Hispanic Black, younger, and individuals with disability
- Lapses less common in those with poor vision or prior PDR treatment
Risk factors for lapse duration
- Older age and PDR treatment predicted shorter lapses
- Residence in distressed areas predicted longer lapses
Post-lapse visual acuity
- Visual acuity worsened after lapses, with greater declines after longer lapses
Original publication
Risk Factors and Consequences of Lapses in Proliferative Diabetic Retinopathy Care in a National Cohort. Diabetes Care. Published 16 September 2025. doi:10.
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