Revised Case Finding Protocol for Dysglycemia in Chile: A Call for Action in Other Populations
Authors' conclusion
This study supports a public health policy to identify more people at risk for cardiovascular disease by implementing a revised case finding protocol for dysglycemia using OGTT in even normal weight patients over 6 years of age when there is at least 1 CMRF. Reanalysis of case finding protocols for cardiometabolic risk in other populations is warranted.
Study context
- Population
- Patients with ≥1 cardiometabolic risk factor (CMRF), oral glucose tolerance test (OGTT) obtained independent of age and BMI; clinical center in Chile (2000–2007)
- Participants
- 4,969 vs 509
- Exposure
- Adults vs Youths
- Adultsn = 4,969
- Youthsn = 509
- Outcome
- Prevalence of dysglycemia (prediabetes and T2D)
Methodological detailsretrospective, medical records, single clinical center
- Retrospective
- Medical records
- Single clinical center
Main finding
As reported in the abstract
Prediabetes, youths
14.1%
95% CI 1.4–17.4
T2D, youths
6.3%
95% CI 4.5–8.7
Prediabetes, adults
36.0%
95% CI 34.7–37.4
T2D, adults
10.7%
95% CI 9.8–11.5
Observational data: associations, not effects.
Further findings
Dysglycemia in underweight and normal-weight adults
- Prediabetes, underweight adults (12.0-36.7)
- 22%
- Prediabetes, normal-weight adults (26.4-32.1)
- 29.2%
- T2D, underweight adults (1.3-16.1)
- 4.9%
- T2D, normal-weight adults (7.2-10.7)
- 8.8%
Dysglycemia in normal-weight youths
- Prediabetes, normal-weight youths (6.7-15.9)
- 10.5%
- T2D, normal-weight youths (1.2-6.6)
- 2.9%
Relation to overweight/obesity
- In adults, but not in youths, most dysglycemia categories were related to overweight/obesity
Original publication
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