Type 1 diabetes

Responses to the Strengths and Difficulties Questionnaire predict HbA1c trajectories in children and adolescents with type 1 diabetes: a population-based study

BMJ Open Diabetes Res CarePublished Population-based cohort study

Authors' conclusion

Caregiver SDQ responses and sociodemographic information may help detect children and adolescents with type 1 diabetes, who need intensive multidisciplinary medical and psychological interventions.

Study context

Population
Danish 2009 national cohort of children and adolescents with T1D; yearly HbA1c 2010–2020; 52% females, mean (SD) age 12.5 (3.3) years, mean diabetes duration 5.2 (3.1) years7,247 HbA1c observations
Participants
835 participants
Exposure
Caregiver Strengths and Difficulties Questionnaire (SDQ) scores as predictors of HbA1c trajectory membership
Outcome
HbA1c trajectory membership predicted by caregiver SDQ scores, adjusted for sex, age at diagnosis, diabetes duration, family structure and caregiver education
Follow-up
2010-2020
Methodological detailsnational cohort, group-based trajectory modeling, multinomial logistic regression
  • National cohort
  • Group-based trajectory modeling
  • Multinomial logistic regression

Main finding

As reported in the abstract

HbA1c trajectory membership by SDQ total difficulties score

Above target, moderate increase then decrease vs On target, gradual decrease: P = 0.0002 · Well above target, large increase then decrease vs On target, gradual decrease: P < 0.0001

Observational data: associations, not effects.

Further findings

SDQ subscale scores

Emotional symptoms predicted trajectories 3 and 4
Conduct problems and hyperactivity/inattention predicted trajectories 2, 3, and 4

Sociodemographic predictors

Single-parent family and low caregiver education level both predicted trajectories 3 and 4

Original publication

Responses to the Strengths and Difficulties Questionnaire predict HbA1c trajectories in children and adolescents with type 1 diabetes: a population-based study. BMJ Open Diabetes Res Care. Published 1 November 2023. doi:10.1136/bmjdrc-2023-003479

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