Relationship between TyG index and the degree of coronary artery lesions in patients with H-type hypertension
Authors' conclusion
The TyG index is an independent risk factor for the degree of coronary stenosis and a better predictor in patients with H-type hypertension combined with coronary artery disease.
Study context
- Population
- Inpatients with hypertension and coronary artery disease, Wuhan Third Hospital, January 1, 2021 to February 1, 2023
- Participants
- 320 inpatients
- Exposure
- TyG index as predictor of coronary stenosis severity
- Outcome
- Severity of coronary stenosis (Gensini score) and number of lesion branches
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
Severe stenosis in H-type hypertension, per TyG index (adjusted)
OR for severe stenosis
OR = 4000, 95% CI 2.411-6.635
p = 0.0001
OR for multivessel disease
OR = 1.862, 95% CI 1.036-3.348
p < 0.0001
Observational data: associations, not effects.
Further findings
Predictive ability of TyG for severe coronary stenosis
- AUC, H-type hypertension
- 0.888, 95% CI 0.838-0.939, p < 0.0001
- AUC, without H-type hypertension
- 0.615, 95% CI 0.494-0.737, p < 0.05
Original publication
Relationship between TyG index and the degree of coronary artery lesions in patients with H-type hypertension. Cardiovasc Diabetol. Published 12 January 2024. doi:10.
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