Relationship between the cumulative exposure to atherogenic index of plasma and ischemic stroke: a retrospective cohort study
Authors' conclusion
High cumulative AIP is associated with a higher risk of ischemic stroke, which implies that the long-term monitoring and maintenance of an appropriate AIP may help prevent such events.
Study context
- Population
- Kailuan Study participants with consecutive health examinations in 2006, 2008 and 2010 and no history of ischemic stroke or cancer
- Participants
- 54,123 participants
- Exposure
- Quartiles of time-weighted cumulative atherogenic index of plasma (AIP), Q2–Q4 vs Q1
- Outcome
- Ischemic stroke
- Follow-up
- Median 11.03 years
Methodological detailsKailuan Study, Cox proportional hazard models
- Kailuan Study
- Cox proportional hazard models
Main finding
As reported in the abstract
Each group vs Q1Hazard ratio (95% CI)
Q2
1.17(1.03–1.32)
Q3
1.33(1.18–1.50)
Q4
1.45(1.28–1.64)
- New ischemic stroke events
- 2,742
Observational data: associations, not effects.
Further findings
- Longer duration of high AIP exposure significantly associated with increased ischemic stroke risk
Original publication
Relationship between the cumulative exposure to atherogenic index of plasma and ischemic stroke: a retrospective cohort study. Cardiovasc Diabetol. Published 15 November 2023. doi:10.
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