Type 2 & other diabetes

Reduced Rate of Hospitalizations for Acute Diabetes Events Before and After FreeStyle Libre ® System Initiation in Some People With Type 2 Diabetes on Insulin-Secretagogue Oral Drug Therapy Without Insulin in France

Diabetes Technol TherPublished Retrospective cohort study

Authors' conclusion

This study suggests the value of the FSL system in reducing ADEs in some people with T2DM in France being treated with insulin-secretagogues without insulin.

Study context

Population
People with T2D on oral insulin-secretagogues without insulin, first FSL reimbursement between August 1, 2017 and December 31, 2018, France
Participants
1,272 people
Exposure
12 months before vs up to 24 months after FreeStyle Libre initiation
Outcome
Hospitalization for any acute diabetes event (ADE): hypoglycemic events, DKA, comas, hyperglycemia-related admissions (ICD-10 codes)
Methodological detailsbefore-after, national claims database (SNDS), exploratory analysis
  • Before-after
  • National claims database (SNDS)
  • Exploratory analysis

Main finding

As reported in the abstract

≥1 hospitalization for any ADE
GroupValueAt 12 monthsAt 24 months
Before FSL7.15%
After FSL2.52%2.52%2.83%

Value

Before FSL7.15%
After FSL2.52%

At 12 months

Before FSL— not stated in the abstract
After FSL2.52%

At 24 months

Before FSL— not stated in the abstract
After FSL2.83%

Observational data: associations, not effects.

Further findings

≥1 hospitalization for any ADE at 24 months — After FSL
2.83%

Admissions for acute diabetes events (ADEs) related to diabetic ketoacidosis (DKA) or other hyperglycemia-related events

Fewer admissions after FSL initiation
−73%

≥1 hospitalization for any ADE at 24 months

Patterns of reduced ADEs persisted after 2 years

Original publication

Reduced Rate of Hospitalizations for Acute Diabetes Events Before and After FreeStyle Libre ® System Initiation in Some People With Type 2 Diabetes on Insulin-Secretagogue Oral Drug Therapy Without Insulin in France. Diabetes Technol Ther. Published 4 July 2024. doi:10.1089/dia.2024.0171

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