A Real-World Prospective Study of the Effectiveness and Safety of Automated Insulin Delivery Compared With Other Modalities of Type 1 Diabetes Treatment During Ramadan Intermittent Fasting
Authors' conclusion
Use of AID is associated with the highest rates of fasting and best glycemic control during Ramadan fasting.
Study context
- Population
- People with T1D who attempted fasting during Ramadan 2022
- Participants
- 294 people
- Exposure
- Automated insulin delivery (AID) vs other T1D treatment modalities during Ramadan fasting
- AIDn = 62
- Conventional pump + continuous glucose monitoring (CGM)n = 37
- Pump + self-monitoring of blood glucose (SMBG)n = 8
- Multiple daily injections (MDI) + CGMn = 155
- MDI + SMBGn = 32
- Outcome
- Median days fasting broken because of diabetes
- Follow-up
- Ramadan
Methodological detailsreal-world
- Real-world
Main finding
As reported in the abstract
P = 0.047
Observational data: associations, not effects.
Further findings
Double target: fast broken ≤2 days because of diabetes and TIR ≥70% · Ramadan
Glycemic metrics (time in range (TIR), glycemia risk index, TBR, TAR) · Ramadan
- AID: significantly greater TIR and lower glycemia risk index, TBR and TAR vs conventional pump and MDI users (both P < 0.05)
Double target: fast broken ≤2 days because of diabetes and TIR ≥70% · Ramadan
- AID vs conventional pump and vs MDI + CGM (both P < 0.05)
Fasting most days of Ramadan (breaking fast ≤2 days)
- AID users twice as likely to complete fasting most days vs MDI + CGM users
- Multivariable logistic regression
Original publication
A Real-World Prospective Study of the Effectiveness and Safety of Automated Insulin Delivery Compared With Other Modalities of Type 1 Diabetes Treatment During Ramadan Intermittent Fasting. Diabetes Care. Published 30 January 2024. doi:10.
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